Cardiac Markers

Coronary Artery Calcium Score — What Your Blood Test Result Means

ScanHealth Learn Cardiac Markers Coronary Artery Calcium Score

Your Arterial Plaque Photograph

The CAC score directly photographs calcium deposits in your coronary arteries via CT scan. Unlike blood tests that measure risk factors, CAC shows the ACTUAL disease. Score of 0 = no calcified plaque (excellent prognosis). Any score >0 = plaque exists. It's the single most powerful predictor of cardiovascular events in asymptomatic people.

What is Coronary Artery Calcium Score?

CAC uses non-contrast cardiac CT with Agatston scoring. Measures calcified (stable) plaque—doesn't detect soft/vulnerable plaque. Scores: 0 = none, 1-99 = mild, 100-399 = moderate, ≥400 = severe. Best for risk reclassification in 40-75 year-olds with intermediate risk.

What High Coronary Artery Calcium Score Means

Established coronary atherosclerosis. >100 = significant disease. >400 = extensive disease with high event risk. This result should drive aggressive prevention.

Common symptoms:

Usually asymptomatic (that's why screening matters) · Angina if significant obstruction · Shortness of breath on exertion

What Low Coronary Artery Calcium Score Means

Score of 0: very low risk. May justify deferring statin in intermediate-risk patients.

Common symptoms:

No symptoms—screening test

Why It Matters

When normal:

Most powerful CVD predictor in asymptomatic individuals

Score 0: >99% 10-year negative predictive value

Reclassifies intermediate-risk patients

Motivates patient adherence

Risks if abnormal:

>0: plaque exists

>100: statin recommended regardless of LDL

>400: high risk, aggressive intervention

Only detects calcified plaque

What Can Cause Abnormal Levels?

Atherosclerosis (cumulative lifetime exposure)

70% likely

CAC reflects decades of risk factor exposure. It's the sum total of plaque buildup.

Age

60% likely

Most men >60 and women >70 have some calcium.

Hypertension

Accelerates plaque formation.

Dyslipidemia

High LDL drives cholesterol deposition.

Diabetes

Accelerated atherosclerosis.

Smoking

Strongest modifiable accelerator.

Family History

Genetic predisposition to early atherosclerosis.

What You Can Do

CAC cannot decrease (calcium is permanent)

Impact: Goal: slow progression and stabilize plaques \u00B7 Timeline: Ongoing

Mediterranean diet, exercise, don't smoke

Impact: Slows plaque progression \u00B7 Timeline: Ongoing

If CAC = 0: repeat in 5-10 years

Impact: Zero score is very reassuring \u00B7 Timeline: 5-10 years

If lifestyle changes aren't enough:

Aggressive LDL/ApoB optimization if CAC >0

Impact: Reduces further cholesterol deposition \u00B7 Timeline: 4-8 weeks

Blood pressure <130/80

Impact: Reduces mechanical stress on plaques \u00B7 Timeline: Ongoing

Recommended retest: Not routine—5 years if baseline zero; no repeat if already >0

Related Markers

ldl apob hscrp lp_a lp_pla2 mpo
Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult your doctor for diagnosis and treatment.

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