Vitamins

Vitamin K — What Your Blood Test Result Means

ScanHealth Learn Vitamins Vitamin K

Your Clotting and Calcium Director

Vitamin K does two critical jobs: it activates clotting proteins that stop you from bleeding, and it activates proteins (osteocalcin, MGP) that direct calcium into your bones and AWAY from your arteries. Without enough vitamin K, calcium ends up in your arteries instead of your bones—arterial calcification and weak bones simultaneously.

What is Vitamin K?

Vitamin K exists as K1 (phylloquinone, from green vegetables) and K2 (menaquinone, from fermented foods and gut bacteria). K1 primarily supports clotting. K2 primarily directs calcium. Both are fat-soluble.

What High Vitamin K Means

Vitamin K toxicity from food is essentially impossible. However, high vitamin K intake interferes with warfarin (blood thinner)—if you're on warfarin, keep vitamin K intake consistent rather than avoiding it.

Common symptoms:

No known toxicity from food forms · Interference with warfarin (maintain consistent intake)

What Low Vitamin K Means

Impaired blood clotting (easy bruising, bleeding) and calcium mismanagement (osteoporosis + arterial calcification). Newborns are at particular risk—that's why they receive a vitamin K shot at birth.

Common symptoms:

Easy bruising · Excessive bleeding from cuts · Blood in urine or stool · Heavy menstrual periods · Osteoporosis (long-term) · Arterial calcification (long-term)

Why It Matters

When normal:

Essential for blood clotting (activates factors II, VII, IX, X)

Directs calcium into bones (activates osteocalcin)

Keeps calcium OUT of arteries (activates MGP)

Supports bone density

Risks if abnormal:

Deficiency: bleeding, bruising, osteoporosis, arterial calcification

Interacts with warfarin (must maintain consistent intake)

Newborns born with minimal stores

What Can Cause Abnormal Levels?

Low Dietary Intake

45% likely

K1 from greens and K2 from fermented foods. People who eat few vegetables and no fermented foods miss both.

Fat Malabsorption

35% likely

Fat-soluble vitamin. Celiac, Crohn's, cholestasis, and pancreatic insufficiency impair absorption.

Antibiotics

Broad-spectrum antibiotics kill gut bacteria that produce vitamin K2.

Warfarin Therapy

Warfarin works BY blocking vitamin K—patients are functionally K-deficient by design.

Liver Disease

The liver makes vitamin K-dependent clotting factors.

What You Can Do

K1 foods: kale, spinach, broccoli, Brussels sprouts, collard greens

Impact: Dark leafy greens are the richest K1 sources \u00B7 Timeline: 2-4 weeks

K2 foods: natto (richest source), hard cheeses, egg yolks, butter

Impact: K2 specifically directs calcium to bones \u00B7 Timeline: 4-8 weeks

Eat with fat for absorption

Impact: Fat-soluble vitamin needs dietary fat \u00B7 Timeline: Immediate

If lifestyle changes aren't enough:

Vitamin K2 (MK-7): 100-200mcg daily

Impact: MK-7 has the longest half-life and best evidence for bone and arterial health \u00B7 Timeline: 3-6 months

Pair with vitamin D (synergistic for calcium management)

Impact: D increases calcium absorption, K2 directs where it goes \u00B7 Timeline: 3-6 months

Recommended retest: 3-6 months

Related Markers

vitamin_d calcium pt_inr osteocalcin
Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult your doctor for diagnosis and treatment.

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